Recent advancements in liquid biopsies have demonstrated the potential of cfDNA as a universal, minimally invasive sample type in cancer prognosis, diagnosis, and prenatal testing 1. In parallel, the ...

A key obstacle in isolating cfDNA is the intricate, labor-intensive manual process required by existing protocols to extract it for downstream processing. This article introduces a unique automated ...

Proximity ligation assay (PLA) to identify HER2-negative breast carcinomas responding in HER-3 targeting agents. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract ...

Cell-free DNA (cfDNA) sequence analysis to screen for fetal aneuploidy can incidentally detect maternal cancer. Additional data are needed to identify DNA-sequencing patterns and other biomarkers that ...

Ever since its first discovery in 1948, circulating cell-free DNA (cfDNA) has captured the attention and imagination of researchers. Its use as a minimally invasive, informative, and dynamic biomarker ...

Researchers found that maternal plasma cell-free DNA methylation patterns in late pregnancy were associated with later autism ...

New England Biolabs has released the Monarch ® Mag Cell-free DNA (cfDNA) Extraction Kit, a bead-based method designed for scalable and reproducible isolation of low abundance cfDNA from plasma, serum, ...

Scientists increasingly appreciate the importance of molecular testing for early cancer detection. 1 Cell free DNA (cfDNA) analysis eliminates the need for invasive tissue biopsies for detection, ...

The much-touted arrival of "precision medicine" promises tailored technologies that help individuals and may also reduce health care costs. New research shows how pregnancy screening can meet both of ...