Small but powerful: Ubiquitin controls the lifespan and distribution of proteins in the cell, but it can also determine their shape, function, or interactions with other cellular components. Ubiquitin ...

Ubiquitin is a protein that is present throughout cellular tissues in eukaryotic organisms which plays a regulatory role in the processes of other proteins and is a versatile molecular signal. First ...

Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome recognizes branched ubiquitin chains. Their finding reveals a multivalent ...

The German Research Foundation (DFG) has now approved a new Collaborative Research Centre in the search for innovative therapies against cancer: Researchers from the Technical University of Munich ...

Researchers have unveiled the crystal structures of UBA6 in complex with either ATP or the ubiquitin-like protein FAT10. These results provide the foundation to study the individual roles of UBA6 ...

In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health. The discovery could lead to ways to improve the treatment of cancer and ...

Researchers from Harvard Medical School (HMS) have discovered how a protein called midnolin plays a key role in degrading many short-lived nuclear proteins. Their study showed that midnolin acts by ...

Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine ...